Sterilization process of cosmetic packaging

Aiming at the situation of China's cosmetics industry in the field of sterilization and disinfection of cosmetic packaging bottles for many years, the old technology has been used and there are defects, drawing on the international advanced disinfection industry, and following the requirements of "GMP Verification Guidelines" and "Disinfection Technical Specifications" formulated by the Ministry of Health. "JZCF-B" series packaging container ozone disinfection system, the disinfection effect is obvious. Cosmetic packaging containers require advanced sterilization process analysis.

Principle of Ozone Sterilization:

The sterilization of ozone belongs to the biochemical oxidation reaction. Ozone oxidation decomposes the enzymes necessary for the oxidation of glucose inside bacteria; it can also directly interact with bacteria and viruses, destroy their cell walls and ribonucleic acid, decompose DNA, RNA, proteins, lipids and polysaccharides and other macromolecular polymers to make bacteria The material metabolism, growth and reproduction process of the cell is destroyed; it can also penetrate the cell membrane tissue, invade the cell membrane and act on the outer membrane lipoprotein and the internal lipopolysaccharide, causing the cell to undergo permeability distortion, leading to the cell's lysis and death, and will die The genetic genes, parasitic strains, parasitic virus particles, bacteriophages, mycoplasma and pyrogens (bacterial virus metabolites, endotoxins) in the bacteria dissolve, denature and die. Throughout the principle of aseptic technology on microorganisms, it can be divided into three types: bacteriostasis, sterilization and bacteriolysis. The application of ozone as a sterilizing agent is bacteriolysis.

In the "Technical Specifications for Disinfection" issued by the Ministry of Health in 1991, the principle of ozone sterilization was also introduced:
"Scientific research shows that ozone has a strong bactericidal effect." "The molecular structure of ozone is unstable at room temperature and pressure, and it quickly decomposes into oxygen (O2) and a single oxygen atom (O). The latter has a strong It is active and has a strong oxidizing effect on bacteria. Ozone oxidation decomposes the enzymes necessary for the oxidation of glucose inside the bacteria, thereby destroying the cell membrane and killing it, and the excess oxygen atoms will recombine themselves into ordinary oxygen molecules (O2). There are no toxic residues, so it is called “non-pollution disinfectant.” It not only has a strong ability to kill various bacteria (including hepatitis virus, E. coli, Pseudomonas aeruginosa and other bacteria), but also kills Mold is also very effective."